Selected publications
- Safina K, van Galen P. New frameworks for hematopoiesis derived from single-cell genomics. https://doi.org/10.1182/blood.2024024006 Blood. (2024)
- Spasic M, Ogayo ER, Parsons AM, Mittendorf EA, van Galen P, McAllister SS. Spectral Flow Cytometry Methods and Pipelines for Comprehensive Immunoprofiling of Human Peripheral Blood and Bone Marrow. Cancer Res Commun. https://doi.org/10.1158/2767-9764.CRC-23-0357 (2024)
- Weng C, Yu F, Yang D, Poeschla M, Liggett LA, Jones MG, Qiu X, Wahlster L, Caulier A, Hussmann JA, Schnell A, Yost KE, Koblan L, Martin-Rufino JD, Min J, Hammond A, Ssozi D, Bueno R, Mallidi H, Kreso A, Escabi J, Rideout WM 3rd, Jacks T, Hormoz S, van Galen P, Weissman JS, Sankaran VG. Deciphering cell states and genealogies of human hematopoiesis. Nature. https://doi.org/10.1038/s41586-024-07066-z (2024)
- Griffin GK, Booth CAG, Togami K, Chung SS, Ssozi D, Verga JA, Bouyssou JM, Lee YS, Shanmugam V, Hornick JL, LeBoeuf NR, Morgan EA, Bernstein BE, Hovestadt V, van Galen P, Lane AA. Ultraviolet Radiation Shapes Dendritic Cell Leukaemia Transformation in the Skin. Nature. http://dx.doi.org/10.1038/s41586-023-06156-8 (2023)
- Lee YS, van Galen P. Mutation signatures reveal clonal evolution. Blood. https://doi.org/10.1182/blood.2022019510 (2023)
- Romine KA, van Galen P. Rise of the Clones: Myelodysplastic Syndrome to Secondary Acute Myeloid Leukemia. Blood Cancer Discov. http://dx.doi.org/10.1158/2643-3230.BCD-22-0046 (2022)
- DePasquale EAK, van Galen P. Plasticity and Immune Evasion in Childhood ALL. Blood. http://dx.doi.org/10.1182/blood.2021015117 (2022)
- DePasquale EAK, Ssozi D, Ainciburu M, Good J, Noel J, Villanueva MA, Couturier CP, Shalek AK, Aranki SF, Mallidi HR, Griffin GK, Lane AA, van Galen P. Single-Cell Multiomics Reveals Clonal T-Cell Expansions and Exhaustion in Blastic Plasmacytoid Dendritic Cell Neoplasm. Front. Immunol. doi:10.3389/fimmu.2022.809414 (2022)
- Miller TE, Lareau CA, Verga JA, DePasquale EAK, Liu V, Ssozi D, Sandor K, Yin Y, Ludwig LS, El Farran CA, Morgan DM, Satpathy AT, Griffin GK, Lane AA, Love JC, Bernstein BE, Sankaran VG, van Galen P. Mitochondrial Variant Enrichment from High-Throughput Single-Cell RNA Sequencing Resolves Clonal Populations. Nat. Biotechnol. doi:10.1038/s41587-022-01210-8 (2022)
- Ainciburu M, Morgan DM, DePasquale EAK, Love JC, Prósper F, van Galen P. WAT3R: recovery of T-cell receptor variable regions from 3′ single-cell RNA-sequencing. Bioinformatics. doi:10.1093/bioinformatics/btac382 (2022)
- Najm FJ, van Galen P. Renewing your HBO1 subscription. Blood 139(6):802-804, doi:10.1182/blood.2021014461 (2022)
- Acosta J, Ssozi D, van Galen P. Single-Cell RNA Sequencing to Disentangle the Blood System. Arterioscler Thromb Vasc Biol 41:1012–1018, doi:10.1161/ATVBAHA.120.314654 (2021)
- Eyler CE, Matsunaga H, Hovestadt V, Vantine SJ, van Galen P, Bernstein BE. Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance. Genome Biol 15;21(1):174, doi:10.1186/s13059-020-02085-1 (2020)
- van Galen P. Decoding the Noncoding Cancer Genome. Cancer Discov 10(5):646-647, doi:10.1158/2159-8290.CD-20-0285 (2020)
- van Galen P, Hovestadt V, Wadsworth Ii MH, Hughes TK, Griffin GK, Battaglia S, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, Pinkus GS, Pozdnyakova O, Galinsky I, Stone RM, Graubert TA, Shalek AK, Aster JC, Lane AA, Bernstein BE. Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. Cell 176, 1265-1281 e1224, doi:10.1016/j.cell.2019.01.031 (2019)
- van Galen P, Mbong N, Kreso A, Schoof EM, Wagenblast E, Ng SWK, Krivdova G, Jin L, Nakauchi H, Dick, JE. Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia. Cell Rep 25, 1109-1117 e1105, doi:10.1016/j.celrep.2018.10.021 (2018)
- van Galen P, Viny AD, Ram O, Ryan RJ, Cotton MJ, Donohue L, Sievers C, Drier Y, Liau BB, Gillespie SM, Carroll KM, Cross MB, Levine RL, Bernstein BE. A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes. Mol Cell 61, 170-180, doi:10.1016/j.molcel.2015.11.003 (2016)
- van Galen P, Kreso A, Mbong N, Kent DG, Fitzmaurice T, Chambers JE, Xie S, Laurenti E, Hermans K, Eppert K, Marciniak SJ, Goodall JC, Green AR, Wouters BG, Wienholds E, Dick JE. The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress. Nature 510, 268-272, doi:10.1038/nature13228 (2014)
- van Galen P, Kreso A, Wienholds E, Laurenti E, Eppert K, Lechman ER, Mbong N, Hermans K, Dobson S, April C, Fan JB, Dick JE. Reduced lymphoid lineage priming promotes human hematopoietic stem cell expansion. Cell Stem Cell 14, 94-106, doi:10.1016/j.stem.2013.11.021 (2014)