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Selected publications
  1. Romine KA, and van Galen P. Rise of the Clones: Myelodysplastic Syndrome to Secondary Acute Myeloid Leukemia. Blood Cancer Discov. (2022)
  2. DePasquale EAK, and van Galen P. Plasticity and Immune Evasion in Childhood ALL. Blood. (2022)
  3. DePasquale EAK, Ssozi D, Ainciburu M, Good J, Noel J, Villanueva MA, Couturier CP, Shalek AK, Aranki SF, Mallidi HR, Griffin GK, Lane AA, and van Galen P. Single-Cell Multiomics Reveals Clonal T-Cell Expansions and Exhaustion in Blastic Plasmacytoid Dendritic Cell Neoplasm. Front. Immunol. doi:10.3389/fimmu.2022.809414 (2022)
  4. Miller TE, Lareau CA, Verga JA, DePasquale EAK, Liu V, Ssozi D, Sandor K, Yin Y, Ludwig LS, El Farran CA, Morgan DM, Satpathy AT, Griffin GK, Lane AA, Love JC, Bernstein BE, Sankaran VG, and van Galen P. Mitochondrial Variant Enrichment from High-Throughput Single-Cell RNA Sequencing Resolves Clonal Populations. Nat. Biotechnol. doi:10.1038/s41587-022-01210-8 (2022)
  5. Ainciburu M, Morgan DM, DePasquale EAK, Love JC, Prósper F, van Galen P. WAT3R: recovery of T-cell receptor variable regions from 3′ single-cell RNA-sequencing. Bioinformatics. doi:10.1093/bioinformatics/btac382 (2022)
  6. Najm FJ, van Galen P. Renewing your HBO1 subscription. Blood 139(6):802-804, doi:10.1182/blood.2021014461 (2022)
  7. Acosta J, Ssozi D, and Van Galen P. Single-Cell RNA Sequencing to Disentangle the Blood System. Arterioscler Thromb Vasc Biol 41:1012–1018, doi:10.1161/ATVBAHA.120.314654 (2021)
  8. Eyler CE, Matsunaga H, Hovestadt V, Vantine SJ, van Galen P, Bernstein BE. Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance. Genome Biol 15;21(1):174, doi:10.1186/s13059-020-02085-1 (2020)
  9. van Galen P. Decoding the Noncoding Cancer Genome. Cancer Discov 10(5):646-647, doi:10.1158/2159-8290.CD-20-0285 (2020)
  10. van Galen P, Hovestadt V, Wadsworth II MH, Hughes TK, Griffin GK, Battaglia S, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, et al. Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. Cell 176, 1265-1281 e1224, doi:10.1016/j.cell.2019.01.031 (2019)
  11. van Galen P, Mbong N, Kreso A, Schoof EM, Wagenblast E, Ng SWK, Krivdova G, Jin L, Nakauchi H, and Dick, JE. Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia. Cell Rep 25, 1109-1117 e1105, doi:10.1016/j.celrep.2018.10.021 (2018)
  12. van Galen P, Viny AD, Ram O, Ryan RJ, Cotton MJ, Donohue L, Sievers C, Drier Y, Liau BB, Gillespie SM, et al. A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes. Mol Cell 61, 170-180, doi:10.1016/j.molcel.2015.11.003 (2016)
  13. van Galen P, Kreso A, Mbong N, Kent DG, Fitzmaurice T, Chambers JE, Xie S, Laurenti E, Hermans K, Eppert K, et al. The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress. Nature 510, 268-272, doi:10.1038/nature13228 (2014)
  14. van Galen P, Kreso A, Wienholds E, Laurenti E, Eppert K, Lechman ER, Mbong N, Hermans K, Dobson S, April C, et al. Reduced lymphoid lineage priming promotes human hematopoietic stem cell expansion. Cell Stem Cell 14, 94-106, doi:10.1016/j.stem.2013.11.021 (2014)
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